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Literature summary extracted from

  • Hatazawa, Y.; Tadaishi, M.; Nagaike, Y.; Morita, A.; Ogawa, Y.; Ezaki, O.; Takai-Igarashi, T.; Kitaura, Y.; Shimomura, Y.; Kamei, Y.; Miura, S.
    PGC-1alpha-mediated branched-chain amino acid metabolism in the skeletal muscle (2014), PLoS ONE, 9, e91006.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.11.4 ATP + [branched-chain a-keto acid dehydrogenase (acetyl-transferring)] Mus musculus
-
 ADP + [branched-chain a-keto acid dehydrogenase (acetyl-transferring)] phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.4 Mus musculus O55028
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.11.4 skeletal muscle
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.4 ATP + [branched-chain a-keto acid dehydrogenase (acetyl-transferring)]
-
 Mus musculus ADP + [branched-chain a-keto acid dehydrogenase (acetyl-transferring)] phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.11.4 BCKDH kinase
-
 Mus musculus
2.7.11.4 BCKDK
-
 Mus musculus

Expression

EC Number Organism Comment Expression
2.7.11.4 Mus musculus overexpression of peroxisome proliferator-activated receptor gamma coactivator-1alpha does not increase the expression of the enzyme additional information